We support the nation’s largest airport-based pathogen genomic surveillance network across 8 international airports—capturing biological intelligence from 135+ countries of origin. Since 2021, over one million international traveler volunteers and 2,600+ wastewater samples havefed a continuously growing dataset that detects emerging health threats, tracks new variants, and generates the biointelligence decision-makers need to respond.

Perimeter operates an international network of biosurveillance nodes across multiple environments in the United States, Africa, the Middle East, Ukraine, and Georgia, working with partners to build their own biological threat picture from the ground up.

Across these programs, we have delivered high-impact surveillance data—from detecting neurovirulent poliovirus and measles on international flights and emerging threats to warfighters and civilians in conflict zones, to monitoring zoonotic spillover risks at human-animal interfaces and AMR genes among microbial communities on farms. This biological intelligence closes critical surveillance gaps that existing global reporting infrastructure has failed to catch.

Your Earliest Early Warning, Validated

Case Study: In August 2025, through the TGS program, we identified novel H3N2 subclade K seven days before it appeared in any public repository. That subclade—known as "super flu"—went on to become the dominant circulating H3N2 strain globally, driving severe flu seasons across multiple countries. Our early detection triggered immediate outreach from the California Department of Public Health for state-level planning. Catching dominant variants this early provides the kind of actionable intelligence that can inform vaccine strain selection and reduce the risk of vaccine mismatch in future seasons.

Case Study: When Mpox Clade Ib emerged in 2024, a 1kb genomic deletion rendered existing field diagnostics ineffective, creating a 30-week global blind spot between emergence and confirmed detection. Within approximately 3 weeks of learning standard diagnostics had failed, our team designed and validated a new pan-clade wastewater PCR assay and deployed it across operational biosurveillance programs in Africa and the Middle East. It is now available as an off-the-shelf kit through the Association of Public Health Laboratories (APHL) and has been validated by Defense Centers for Public Health-Aberdeen.

Having Perimeter infrastructure in place enables early detection when new variants evade existing diagnostics, rapid access to newly developed assays, and reduced time between detection and response. Our systems close gaps and fill blind spots before threats become crises.

Tailored to Mission Needs

At a premier U.S. military treatment facility, our proactive biosurveillance program detected vancomycin-resistant Enterococci (VRE) a full week before clinical identification of patient infection. By mapping sequencing data to specific hospital wings, this surveillance provided early warning of hospital-acquired infections and localized AMR patterns. This data can empower clinicians to optimize antibiotic prescribing and enable administrators to proactively manage staffing and resources.

Beyond hospitals, these tools can apply across military infrastructure including installations, forward-operating bases, and ships, providing commanders with early warning to mitigate Disease and Non-Battle Injuries (DNBI) and protect force health and readiness. They can also be deployed in mass gatherings, clinical settings, commercial environments, and other assets to mitigate operational risks and safeguard health.